السيرة الذاتية والمؤهلات العلمية
العنوان | العيادة: Ethianum Heidelberg، Voßstr. 6، 69115 Heidelberg |
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تاريخ الميلاد: | 27.05.1950 |
مكان الميلاد: | شتوتغارت، بادن-فورتمبيرغ |
الحالة الاجتماعية: | متزوج، لديه طفل واحد |
التعليم المدرسي والجامعي
1969 | High school diploma (with honors); Albert Schweitzer Gymnasium Leonberg, Baden Württemberg |
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1969-1970 | University of Stuttgart, Chemistry |
1970-1975 | University of Heidelberg, Medicine |
9.12.1975 | State examination in medicine |
16.12.1975 | Doctoral thesis (magna cum laude) Title: Renal Excretion of Cyclic AMP in Secondary Hyperparathyroidism |
1976 | University of Tübingen, Biochemistry |
التدريب بعد الدكتوراه، التعيينات السريرية والمسيرة الأكاديمية
1976-1977 | Medical assistant Medical Clinic. |
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1977-1979 | Research Fellow (Deutsche Forschungsgemeinschaft) Alcohol Research and Treatment Centre, V.A. Medical Centre and Mount Sinai School of Medicine (City University of New York), New York, USA |
12.06.1979 | American state examination (ECFMG) |
1979-1985 | Assistant Physician, Medical Clinic (Gastroenterology), Heidelberg University, Director: Prof. Dr. B. Kommerell |
21.12.1983 | Specialist in internal medicine |
26.8.1985 | Gastroenterology specialist |
1986-1991 | Senior Physician, Medical Clinic (Gastroenterology) (Director: Prof. Dr. B. Kommerell) and Medical Polyclinic (Director: Prof. Dr. W. Hunstein), Heidelberg University. |
1991-2020 | Director of the Medical Clinic (Gastroenterology), Salem Hospital, Heidelberg. |
2006-2020 | Director of the Alcohol Research Center (CAR) at Heidelberg University |
Seit 2020 | Director of the Laboratory for Alcohol Research, Liver Diseases, Nutrition, Salem Hospital, Heidelberg |
From 2022 to 2024 | Chief Executive Officer (CEO) of the Board of Directors, City Mission Heidelberg, including Salem Medical Center and St. Vincentius Hospital |
التعيينات الأكاديمية
1970-1979 | Research Fellow (German Research Foundation), Alcohol Research and Treatment Centre, V.A. Medical Centre, Bronx, New York und Mount Sinai Medical Centre, New York, USA (Prof. Dr. Charles S. Lieber) |
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19.7.1984 | Habilitation internal medicine (Experimental Studies on the cocarcinogenic effects of ethanol) |
14.2.1985 | Inaugural lecture (Pathogenesis of colorectal cancer) |
1986 | Gerhard Katsch Fellowship of the German Society of Gastroenterology |
1986 | Gerhard Katsch Fellowship of the German Society of Gastroenterology |
1991 | Asche Fellowship of the German Association of Gastroenterology |
27.9.1991 | APL Professor, University of Heidelberg |
16.2.2004 | Honorary Professorship Tongji Medical College, Huazhong University Wuhan, People's Republic of China |
17.7.2007 | Honorary professor of internal medicine, gastroenterology, and alcohol research with professorial status at Heidelberg University |
2008 | Fellow of the American Gastroenterological Association |
المنح
1977-1979 | Postdoc Research Grant, German Research Foundation. Research Fellow, Alcohol Research and Treatment Centre, Bronx, New York, USA |
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1981 | DAAD Grant: St. Marks Hospital, London |
1981-1983 | Deutsche Forschungsgemeinschaft. Grant (Se 333/1-4) Alkohol und Gastrointestinaltrakt |
1986-1988 | German Research Foundation. Grant (Se 333/1-4) Alcohol and the gastrointestinal tract |
1986 | Gerhard Katsch Academic Foundation (1.1.-30.4.1986) |
1990 | Asche Research Fellowship (Department of Gastroenterology and Nutrition, Nutrition Research Center, Tufts University, Boston, USA) |
1993, 1996 | Biomed and Health Research (Biomed 1) Grand of the European |
1994-1999 | British-German Academic Research Collaboration (ARC), |
1999-2000 | Scientific Research Promotionprogram, Medical Faculty, University of Heidelberg (Alcohol induced pancreatic toxicity) Project 121/1999. In colaboration with the Department of Surgery, University of Heidelberg |
2007-2012 | Research grant from the Dietmar Hopp Foundation: Alcohol and Cancer (€517,000) |
2012-2015 | Continued Dietmar Hopp Foundation Alcohol and Cancer (€198,000) |
2009-2014 | Research grant from the Manfred Lautenschläger Foundation (Pathophysiological mechanisms of alcoholic liver disease) (€250,000) |
2010-2013 | Interdisciplinary Scientific Program (National Cancer Center Heidelberg). DNA methylation as a biomarker for molecular diagnostics in human colon cancer (€100,000). Together with PD Dr. H Linhart |
2010-2014 | Research grant from the Manfred Lautenschläger Foundation: Alcohol, hepatocellular damage, and cancer (€237,000) Together with Prof. Dr. S. Mueller. |
2011-2016 | NIAAA Grant (GWAS on Alcohol and Liver Cirrhosis). Global Cooperative study (PI : Timothy Morgan, USA) ($ 2.600.000) |
2016-2018 | Research Grant: Octapharma Heidelberg: The role of CYP2E1 in Alcoholic Liver Disease (€ 300.000) |
2017 | NIH Grant (Alcohol and Colorectal Cancer): Cooperative Study (PI: Vasilis Vasiliou, New Haven, USA |
الدراسات السريرية
1984 | Walther and Christine Richtzenhain Prize |
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1985 | St. Gallen Alcohol Research Prize |
1986 | Homburg Prize |
1987 | Hans-Adolf Krebs Prize |
1990 | Asche Research grant from the German Society for Digestive and Metabolic Diseases |
1992 | Recognition of scientific work on the topic of ALCOHOL AND CANCER on the front page of Cancer Research (52: 3831, 1992). |
1993 | Invitation to the 86th Nobel Symposium ‚Towards a molecular base of alcohol use and abuse‘, Karolinska-Institute, Stockholm, Schweden (19.-23. September 1993) |
1996 | Karls-Medaille, Karls Universität Prag, Tschechien |
1997 | Recognition of scientific work on the subject of ALCOHOL AND CANCER on the front page of the International Journal of Oncology (July 1997 issue) |
2008 | Fellow of the American Gastroenterologic Association (AGA) |
2010 | Hiromasa Ishii Memorial Prize International Society for Biomedical Research on Alcoholism, Paris, September 2010 |
2011 | Invited speech on the death of Professor Hiromasha Ishii (6th International Symposium on ALPD and Cirrhosis:A tribute to the late Professor Hiromasha Ishii, Fukuoka, Japan |
2013 | European Alcohol Research Prize of the European Society for Biomedical Research on Alcoholism (ESBRA), Warsaw, September 2013 |
2017 | Awarded the Charles University Silver Medal, Prague, Czechia |
2017 | Panel Member Gordon Conference on Alcoholic Liver Disease, Ventura, CA, USA (march) |
2018 | Invitation from NATURE: PRIMER magazine on the topic of alcoholic liver disease |
2019 | The Charles Lieber Memorial Lecture 2019 (The role of CYP2E1 in alcohol-related cancer and alcohol-related liver disease), Lille, France, September 2019 |
2021 | The European Alcohol Prize of the European Society for Biomedical Research on Alcoholism, endowed with €25,000 and funded by the Lautenschläger Foundation, has been renamed and is now called “The ESBRA Helmut Seitz Prize for Alcohol Research.” |
2022 | Günter and Ursula Rauscher Prize for Medical Prevention |
2022 | Tobacco Off Prize from the International Society for Biomedical Research on Alcoholism (ISBRA), Krakow, Poland, September 2022 |
2023 | Member of the Jellinek Prize Selection Committee |
الجوائز والتكريمات
1984 | Walther and Christine Richtzenhain Prize |
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1985 | St. Gallen Alcohol Research Prize |
1986 | Homburg Prize |
1987 | Hans-Adolf Krebs Prize |
1990 | Asche Research grant from the German Society for Digestive and Metabolic Diseases |
1992 | Recognition of scientific work on the topic of ALCOHOL AND CANCER on the front page of Cancer Research (52: 3831, 1992). |
1993 | Invitation to the 86th Nobel Symposium ‚Towards a molecular base of alcohol use and abuse‘, Karolinska-Institute, Stockholm, Schweden (19.-23. September 1993) |
1996 | Karls-Medaille, Karls Universität Prag, Tschechien |
1997 | Recognition of scientific work on the subject of ALCOHOL AND CANCER on the front page of the International Journal of Oncology (July 1997 issue) |
2008 | Fellow of the American Gastroenterologic Association (AGA) |
2010 | Hiromasa Ishii Memorial Prize International Society for Biomedical Research on Alcoholism, Paris, September 2010 |
2011 | Invited speech on the death of Professor Hiromasha Ishii (6th International Symposium on ALPD and Cirrhosis:A tribute to the late Professor Hiromasha Ishii, Fukuoka, Japan |
2013 | European Alcohol Research Prize of the European Society for Biomedical Research on Alcoholism (ESBRA), Warsaw, September 2013 |
2017 | Awarded the Charles University Silver Medal, Prague, Czechia |
2017 | Panel Member Gordon Conference on Alcoholic Liver Disease, Ventura, CA, USA (march) |
2018 | Invitation from NATURE: PRIMER magazine on the topic of alcoholic liver disease |
2019 | The Charles Lieber Memorial Lecture 2019 (The role of CYP2E1 in alcohol-related cancer and alcohol-related liver disease), Lille, France, September 2019 |
2021 | The European Alcohol Prize of the European Society for Biomedical Research on Alcoholism, endowed with €25,000 and funded by the Lautenschläger Foundation, has been renamed and is now called “The ESBRA Helmut Seitz Prize for Alcohol Research.” |
2022 | Günter and Ursula Rauscher Prize for Medical Prevention |
2022 | Tobacco Off Prize from the International Society for Biomedical Research on Alcoholism (ISBRA), Krakow, Poland, September 2022 |
2023 | Member of the Jellinek Prize Selection Committee |
أستاذية زائرة
1986-2005 | Nutrition and Oncology Lab., Human Nutrition Research Centre on Aging, Tufts University, Boston USA (yearly) |
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1987 | Dept. Medicine, University of Illinois of Chicago, USA |
1988, 2004 | Tongji Medical College, Huazhong University, Wuhan, PR China |
1991-2015 | Dept. Of Preventive Medicine, University of Zurich, Switzerland (yearly) |
1993 | Department of Biochemistry and Molecular Biology, Autonomous University of Barcelona, Spain |
1994, 2002 | Research Unit of Substance Abuse Medicine, Biomedicum Helsinki, University of Helsinki, Finland |
1995 | Dept. Medicine, La Jolla University, Chicago USA |
1995 | Laboratoire de Biochemie – Nutrition, University de Brest, France |
2000 | Arab University Beirut/Lebanon (2 weeks course) |
2006 | Alcohol Research and Treatment Centre, VA Medical Centre, Bronx, New York, USA |
2013 | University of Tennessee Health Science Centre, Memphis USA |
محاضرات حول أحدث التطورات
2003 | Plenary Lecture at the ESBRA Congress, Prague, Czech Republic on Alcohol and Cancer. 11.-14.September 2003 |
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2004 | Alcoholic Liver Disease: New concepts in pathogenesis |
2004 | Alcoholic Liver Disease: Alcohol or Genes? |
2006 | Alcohol and carcinogenesis |
2007 | Molecular mechanisms of alcohol mediated carcinogenesis (state-of-the art lecture) |
2008 | Molecular mechanisms of alcohol mediated carcinogenesis |
2013 | Alcohol and Cancer |
2014 | Invitation Annual Congress of the Guatemala Society for Gastroenterology |
2015 | Alcoholic liver diseases. |
2016 | Representative of the United European Gastroenterology in Suzou, VR China, New Developments in Gastroenterology, Suzou, September 2016 |
2017 | Alcohol and cancer. International Congress Gastroenterology, University of Padova, Italy, Januar 2017 |
2017 | Alcohol and cancer. Congress of the Italian Gastroenterologic Society, Rom, Oktober 2017 |
2018 | Alcoholic Liver Disease. Titisee Symposium, Februar 2018 |
2018 | Alcoholic Liver Disease. Romanian German Society for Gastroenterology, Brashov, Rumänien, April 2018 |
2019 | The role of cytochrome P4502E1 in alcoholic liver disease and cancer. ESBRA Congress, Lille, France, September 2019 |
2020 | Alcohol and Cancer, Albatros 14th International Congress on Addiction Paris, France, October 2020 |
2021 | Postgraduate course: How much alcohol can we drink, International Congress (EASL), remote event, April 2021 |
2021 | RSA Lecture Series: Alcohol and Cancer, Youtube February 2021 |
2022 | The role of cytochrome P-450 in alcohol-related liver disease: from the laboratory to the bedside, 21st ISBRA Congress, Krakow, Poland, September 17–20, 2022 |
2024 | Gustave Roussy Lecture 2024 Alcohol and Cancer: The Role of Cytochrome P4502E1 in Alcohol-Related Cancer and Alcohol-Related Liver Disease, December 15, 2024, Villejuive, Paris, France |
الكراسي وعضوية أعضاء هيئة التدريس
1988 | Alcohol and Cancer |
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2000 | Alcohol and gastroenterological diseases. |
2001 | The role of Gastric Emptying in First Pass Metabolism of Ethanol. |
2002 | Laboratory, clinic, and progression of NASH and ASH. |
2002 | Alcohol-related diseases in gastroenterology. Working session chaired by P. Schuppan, H.K. Seitz). 57th Conference of the German Society for Digestive and Metabolic Diseases. Bonn, Sept. 20, 2002. |
2004 | Alcohol and Cancer (Symposium Chair), Annual Meeting of the German Cancer Society, Berlin, February 27, 2004 |
2004 | Alcohol and retinoids. Alcohol workshop (chaired by Prof. Singer) Annual Conference of the German Society for Digestive and Metabolic Diseases. Leipzig, September 1, 2004 |
2004 | Alcoholic Liver Disease: From Pathophysiology to Therapy |
2004 | Alcohol and the gastrointestinal tract. In: Alcohol related pathology from head to toe, a synopsis of alcohol-related pathology which also celebrates the work and retiremend of Prof. Timothy J. Peters (Chair and organizer). ISBRA Satellite meeting 2004, Heidelberg, 29th September 2004 |
2004 | ADH1C polymorphism and risk of cancer. In. From alcohol toxicity to treatment. Charles Lieber Alumni Meeting 2004 ISBRA Satellite Meeting 2004 (Chair and Organizer). Mannheim 2nd October 2004 |
2004 | Alcohol as a co-carcinogen in the gastrointestinal tract. Symposium: Alcohol as a cofactor in gastrointestinal diseases (chaired with Prof. Schuppan), Annual Meeting of the German Society for Digestive and Metabolic Diseases. Leipzig, October 2. |
2004 | Cancer of the upper aerodigestive tract and the large intestine: possible mechanisms. NIH Conference, mechanisms of alcohol associated cancers Chair. 6Th/7th October 2004 Bethesda, Maryland USA. |
2007 | Member of an International panel on Alcohol and Cancer, International Agency for Reseach and Cancer (IARC), Lyon France, 6th-13th Feb. 2007 |
2008 | Alcoholic Steatohepatitis: established and experimental therapy. Chair together with C.P. Day Workshop, European Association for the study of the liver (EASL) Milano, Italy 24th .- 26th April 2008 |
2009 | Member of a scientific delegation of Baden Württemberg to the |
2010 | Invitation for the 1st Charles Lieber Memorial Symposium during the RSA Congress in San Antonio, Texas USA |
2010 | ISBRA Congress, Paris 11th to 15th September 2010 |
2010 | German Society for Gastroenterology, DVGS, Stuttgart, September 16, 2010 |
2010 | Extramural Advisor for the NIAAA on Alcohol and Cancer, |
2010 | Faculty Member of the United European Gastroenterology Week |
2010 | Member of scientific delegation of Baden Württemberg to |
2010 | Faculty Member of the European Association for the Study of the Liver (EASL), Vienna |
2011 | Member of a European Panel of the European Association for the Study of the Liver (EASL) for the Guidelines of Alcoholic Liver Disease |
2011 | Faculty Member of the United European Gastroenterology Week (UEGW) in Stockholm, Sweden |
2011 | Faculty Member, Ann. Congress of the European Association for the study of the liver (EASL) Berlin, April 2011 |
2012 | Faculty Member of the European Association for the study of the Liver (EASL) Barcelona, Spain, April 2012 |
2012 | Invitation as a ad hoc extramural Advisor to the NIAAA for Alcoholic Hepatitis, Rockville, Maryland, USA 7th to 8th February 2012 |
2012 | Invitation 2012 ISBRA Satellite Symposium Kyoto, Japan |
2012 | ISBRA Congress, Sapporo, Japan |
2013 | Faculty Member of the European Association for the Study of the Liver (EASL) Amsterdam, The Netherlands, 24th - 28th April 2013 |
2013 | Faculty Member of the United European Gastroenterology Week |
2013 | DGVS, Nürnberg |
2014 | Member of Dissertation Board, Maastrich, The Netherlands |
2014 | Faculty Member of the European Association for the Study of the Liver (EASL) London, UK, 9th – 13th April 2014 |
2014 | Guidelines NAFLD, German Society for Digestive and Metabolic Diseases |
2014 | Faculty Member of the United European Gastroenterology Week |
2015 | ESBRA Valencia, Spain |
2016 | ISBRA, Berlin |
2016 | Representive of the United European Gastroenterology Week (UEWG), Souzou, VR China, September 2016 |
2016 | Faculty Member of the United European Gastroenterology Week |
2017 | The International Liver Meeting, Amsterdam, The Netherlands |
2017 | Gordon Conference on Alcoholic Liver Disease, Ventura, CA, USA March 2017 |
2022 | Charles Lieber Symposium, RSA, Crakow, Poland |
2010-2023 | Organizer and Speaker, Charles Lieber Memorial Symposium (RSA):San Antonio (2010), Atlanta (2011), San Francisco (2012), Orlando (2013), Seattle (2014), San Antonio (2015), New Orleans (2016), Denver (2017), San Diego (2018), Minneapolis (2019), Virtual (2021), Orlando (2022), Bellevue (2023), Minneapolis (2024) |
