Curriculum vitae of Prof. Dr. med. Prof. h.c. (VRC) Helmut K. Seitz

High school diploma (with honors); Albert Schweitzer Gymnasium Leonberg, Baden Württemberg

University of Stuttgart, Chemistry

University of Heidelberg, Medicine

State examination in medicine

Doctoral thesis (magna cum laude)

Title: Renal Excretion of Cyclic AMP in Secondary Hyperparathyroidism

University of Tübingen, Biochemistry

Medical assistant Medical Clinic.
Surgical Clinic, Pathological Institute, University of Heidelberg.

Research Fellow (Deutsche Forschungsgemeinschaft)

Alcohol Research and Treatment Centre, V.A. Medical Centre and Mount Sinai School of Medicine (City University of New York), New York, USA
Direktor: Charles S. Lieber, M.D.

American state examination (ECFMG)

Assistant Physician, Medical Clinic (Gastroenterology), Heidelberg University, Director: Prof. Dr. B. Kommerell

Specialist in internal medicine

Gastroenterology specialist

Senior Physician, Medical Clinic (Gastroenterology) (Director: Prof. Dr. B. Kommerell) and Medical Polyclinic (Director: Prof. Dr. W. Hunstein), Heidelberg University.

Director of the Medical Clinic (Gastroenterology), Salem Hospital, Heidelberg.

Director of the Alcohol Research Center (CAR) at Heidelberg University

Director of the Laboratory for Alcohol Research, Liver Diseases, Nutrition, Salem Hospital, Heidelberg

Chief Executive Officer (CEO) of the Board of Directors, City Mission Heidelberg, including Salem Medical Center and St. Vincentius Hospital

Research Fellow (German Research Foundation), Alcohol Research and Treatment Centre, V.A. Medical Centre, Bronx, New York und Mount Sinai Medical Centre, New York, USA (Prof. Dr. Charles S. Lieber)

Habilitation internal medicine (Experimental Studies on the cocarcinogenic effects of ethanol)

Inaugural lecture (Pathogenesis of colorectal cancer)

Gerhard Katsch Fellowship of the German Society of Gastroenterology
Northwick Park Hospital, MRC, London, Great Britain

Gerhard Katsch Fellowship of the German Society of Gastroenterology
USDA, Human Nutrition Research Centre. On Aging, Tufts University Boston, MA, USA

Asche Fellowship of the German Association of Gastroenterology
USDA, Human Nutrition Research Centre On Aging, Tufts University, Boston, MA, USA

APL Professor, University of Heidelberg

Honorary Professorship Tongji Medical College, Huazhong University Wuhan, People's Republic of China

Honorary professor of internal medicine, gastroenterology, and alcohol research with professorial status at Heidelberg University

Fellow of the American Gastroenterological Association

Postdoc Research Grant, German Research Foundation. Research Fellow, Alcohol Research and Treatment Centre, Bronx, New York, USA

DAAD Grant: St. Marks Hospital, London

Deutsche Forschungsgemeinschaft. Grant (Se 333/1-4) Alkohol und Gastrointestinaltrakt

German Research Foundation. Grant (Se 333/1-4) Alcohol and the gastrointestinal tract

Gerhard Katsch Academic Foundation (1.1.-30.4.1986)
1. Div. of Cell Biology, Medical Research Ctr., Northwick Park Hospital, Harrow, U.K. (Director: T.J. Peters, M.D.)
2. USDA, Huan Nutrition Research Ctr. on Aging and New England Medical Ctr., Tufts University, Boston, USA

Asche Research Fellowship (Department of Gastroenterology and Nutrition, Nutrition Research Center, Tufts University, Boston, USA)
Title: Alcohol dehydrogenase in the human stomach

Biomed and Health Research (Biomed 1) Grand of the European
Community: Genetics and Biochemical Determinants of Alcohol Toxicity and Addiction.
Together with:
1. Department of Biochemistry and Molecular Biology, Autonomous University of Barcelona, Spain
2. Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
3. Department of Biochemistry and Molecular Biology, University of Bordeau, Bordeau, France

British-German Academic Research Collaboration (ARC),
Prof. Timothy Peters, Dept. of Clinical Biochemistry, Kings College, London, UK

Scientific Research Promotionprogram, Medical Faculty, University of Heidelberg (Alcohol induced pancreatic toxicity) Project 121/1999. In colaboration with the Department of Surgery, University of Heidelberg

Research grant from the Dietmar Hopp Foundation: Alcohol and Cancer (€517,000)

Continued Dietmar Hopp Foundation Alcohol and Cancer (€198,000)

Research grant from the Manfred Lautenschläger Foundation (Pathophysiological mechanisms of alcoholic liver disease) (€250,000)

Interdisciplinary Scientific Program (National Cancer Center Heidelberg). DNA methylation as a biomarker for molecular diagnostics in human colon cancer (€100,000). Together with PD Dr. H Linhart

Research grant from the Manfred Lautenschläger Foundation: Alcohol, hepatocellular damage, and cancer (€237,000) Together with Prof. Dr. S. Mueller.

NIAAA Grant (GWAS on Alcohol and Liver Cirrhosis). Global Cooperative study (PI : Timothy Morgan, USA) ($ 2.600.000)
Together with
1. Drug Health Services, Prince Alfred Hospital, Univ. Sydney Australia (P.Haber, D.Seth)
2. Department of Visceral Surgery and Medicine, Univ. Bern, Switzerland (F. Stickel)
3. Inst. Cellular Medicine, Univ. Newcastle upon Trent, UK (C. Day)
4. Gastroenterology Section, VA Long Beach Healthcare System, Long Beach, USA (T. Morgan)
5. Department of Psychology, Purdue School of Science, Indiana University, Indianapolis, USA (L. Lumeng)
6. Department of Hepato-Gastroenterology, Univ. Of Lille, France (P. Mathurin)

Research Grant: Octapharma Heidelberg: The role of CYP2E1 in Alcoholic Liver Disease (€ 300.000)

NIH Grant (Alcohol and Colorectal Cancer): Cooperative Study (PI: Vasilis Vasiliou, New Haven, USA

Sensitivity and specificity of Ki-ras PCR in pancreatic tumors Cooperation partners: Department of Hematology, University of Homburg/Saar

Influence of essential phospholipids and alpha interferon on the progression of hepatitis C. Cooperation partner: Nattermann, Cologne.

Influence of silymarin on mortality in alcoholic liver cirrhosis: placebo-controlled, randomized, multicenter, double-blind study. (PI: Seitz HK/ Fleig W).

Magnetic spectroscopy studies in alcoholic hepatitis. Cooperation partner: DKFZ Heidelberg.
Conservative vs. surgical treatment of acute cholecystitis. Cooperation partner: Heidelberg University Hospital, Department of Surgery.

International GWAS study: Alcoholic liver cirrhosis (PI T. Morgan, USA)

Epigenetics in colorectal cancer. Cooperation partners: NCT and DKFZ Heidelberg

Transient elastography in alcoholic liver disease

Influence of chloromethiazole on the course of alcoholic liver disease (PI Seitz HK, Haefeli W).

Walther and Christine Richtzenhain Prize
German Cancer Research Center (DKFZ), Heidelberg
Titel: Enhancement of 1,2-dimethyl-hydrazine induced rectal carcinogenesis following chronic ethanol consumption in the rat

St. Gallen Alcohol Research Prize
St. Gallen, Switzerland
Title: Experimental animal studies on the cocarcinogenic effect of alcohol on the rectum

Homburg Prize
Regensburg College for Continuing Medical Education, Regensburg
Title: Alcohol and Cocarcinogenesis

Hans-Adolf Krebs Prize
German Nutrition Society, Munich
Titel: Studies on the influence of age on the metabolism and the toxicity of alcohol taking into consideration vitamins A and E

Asche Research grant from the German Society for Digestive and Metabolic Diseases
Titel: Studies on alcohol dehydrogenase in the human gut: influence of age and chronic-atrophic gastritis on the first pass metabolism of ethanol in man

Recognition of scientific work on the topic of ALCOHOL AND CANCER on the front page of Cancer Research (52: 3831, 1992).

Invitation to the 86th Nobel Symposium ‚Towards a molecular base of alcohol use and abuse‘, Karolinska-Institute, Stockholm, Schweden (19.-23. September 1993)

Karls-Medaille, Karls Universität Prag, Tschechien

Recognition of scientific work on the subject of ALCOHOL AND CANCER on the front page of the International Journal of Oncology (July 1997 issue)

Fellow of the American Gastroenterologic Association (AGA)

Hiromasa Ishii Memorial Prize International Society for Biomedical Research on Alcoholism, Paris, September 2010

Invited speech on the death of Professor Hiromasha Ishii (6th International Symposium on ALPD and Cirrhosis:A tribute to the late Professor Hiromasha Ishii, Fukuoka, Japan

European Alcohol Research Prize of the European Society for Biomedical Research on Alcoholism (ESBRA), Warsaw, September 2013

Awarded the Charles University Silver Medal, Prague, Czechia

Panel Member Gordon Conference on Alcoholic Liver Disease, Ventura, CA, USA (march)

Invitation from NATURE: PRIMER magazine on the topic of alcoholic liver disease

The Charles Lieber Memorial Lecture 2019 (The role of CYP2E1 in alcohol-related cancer and alcohol-related liver disease), Lille, France, September 2019

The European Alcohol Prize of the European Society for Biomedical Research on Alcoholism, endowed with €25,000 and funded by the Lautenschläger Foundation, has been renamed and is now called “The ESBRA Helmut Seitz Prize for Alcohol Research.”

Günter and Ursula Rauscher Prize for Medical Prevention

Tobacco Off Prize from the International Society for Biomedical Research on Alcoholism (ISBRA), Krakow, Poland, September 2022

Member of the Jellinek Prize Selection Committee

2003

Plenary Lecture at the ESBRA Congress, Prague, Czech Republic on Alcohol and Cancer. 11.-14.September 2003

2004

Alcoholic Liver Disease: New concepts in pathogenesis
ESBRA Nordman Award Meeting, 2004 Alcohol and Cannabis from basic to clinical Research. Lisabon, Portugal 28./29. Mai 2004

2004

Alcoholic Liver Disease: Alcohol or Genes?
European Society of Parenteral and Enteral Nutrition (ESPEN) Lisabon, Portugal 10. September 2004

2006 

Alcohol and carcinogenesis
State of the Art Lecture. VA Medical Center, Bronx, New York, USA, 25.Mai 2006

2007

Molecular mechanisms of alcohol mediated carcinogenesis (state-of-the art lecture)
European Society for Laboratory Medicine Prag, Czech Republic 16.September 2007

2008

Molecular mechanisms of alcohol mediated carcinogenesis
14. ISBRA Congress, Washington DC 29.Juni 2008

2013

Alcohol and Cancer
14th ESBRA Congress, Warsaw, Poland 8.-11.September 2013

2014

Invitation Annual Congress of the Guatemala Society for Gastroenterology
Antigua, Guatemala 24.-27.Juli 2014

2015

Alcoholic liver diseases.
Kaplan Centre, Rehovot, Israel, Januar 2015

2016

Representative of the United European Gastroenterology in Suzou, VR China, New Developments in Gastroenterology, Suzou, September 2016

2017

Alcohol and cancer. International Congress Gastroenterology, University of Padova, Italy, Januar 2017

2017

Alcohol and cancer. Congress of the Italian Gastroenterologic Society, Rom, Oktober 2017

2018

Alcoholic Liver Disease. Titisee Symposium, Februar 2018

2018

Alcoholic Liver Disease. Romanian German Society for Gastroenterology, Brashov, Rumänien, April 2018

2019

The role of cytochrome P4502E1 in alcoholic liver disease and cancer. ESBRA Congress, Lille, France, September 2019

2020

Alcohol and Cancer, Albatros 14th International Congress on Addiction Paris, France, October 2020

2021

Postgraduate course: How much alcohol can we drink, International Congress (EASL), remote event, April 2021

2021

RSA Lecture Series: Alcohol and Cancer, Youtube February 2021

2022

The role of cytochrome P-450 in alcohol-related liver disease: from the laboratory to the bedside, 21st ISBRA Congress, Krakow, Poland, September 17–20, 2022

2024

Gustave Roussy Lecture 2024 Alcohol and Cancer: The Role of Cytochrome P4502E1 in Alcohol-Related Cancer and Alcohol-Related Liver Disease, December 15, 2024, Villejuive, Paris, France

Alcohol and Cancer
IV. Congress of the International Society for Biomedical Research on Alcoholism (ISBRA), Chairman and Organizer 11ft he Workshop Kyoto, Japan, June 1988

Alcohol and gastroenterological diseases.
Symposium Annual Meeting of the German Society for Digestive and Metabolic Diseases (Chair: H.K. Seit, M.Singer) Hamburg, September 15, 2000

The role of Gastric Emptying in First Pass Metabolism of Ethanol.
Symposium First Pass Metabolism of Ethanol (Vorsitz: Yin Taipeh, H.K. Seitz), 8th ESBRA Congress. Paris/Frankreich 15.-18. Sept. 2001

Laboratory, clinic, and progression of NASH and ASH.
Symposium on NASH and ASH. Similarities and differences (Chair: Plauth/Seitz) German Congress of Internal Medicine. Wiesbaden, April 9, 2002

Alcohol-related diseases in gastroenterology. Working session chaired by P. Schuppan, H.K. Seitz). 57th Conference of the German Society for Digestive and Metabolic Diseases. Bonn, Sept. 20, 2002.

Alcohol and Cancer (Symposium Chair), Annual Meeting of the German Cancer Society, Berlin, February 27, 2004

Alcohol and retinoids. Alcohol workshop (chaired by Prof. Singer) Annual Conference of the German Society for Digestive and Metabolic Diseases. Leipzig, September 1, 2004

Alcoholic Liver Disease: From Pathophysiology to Therapy
(Vorsitz mit Charles Lieber). International Society for Biomedical Research on Alcoholism. 12th World congress on Biomedical Research Heidelberg/Mannheim 29th Sept – 02nd Oct. 2004

Alcohol and the gastrointestinal tract. In: Alcohol related pathology from head to toe, a synopsis of alcohol-related pathology which also celebrates the work and retiremend of Prof. Timothy J. Peters (Chair and organizer). ISBRA Satellite meeting 2004, Heidelberg, 29th September 2004

ADH1C polymorphism and risk of cancer. In. From alcohol toxicity to treatment. Charles Lieber Alumni Meeting 2004 ISBRA Satellite Meeting 2004 (Chair and Organizer). Mannheim 2nd October 2004

Alcohol as a co-carcinogen in the gastrointestinal tract. Symposium: Alcohol as a cofactor in gastrointestinal diseases (chaired with Prof. Schuppan), Annual Meeting of the German Society for Digestive and Metabolic Diseases. Leipzig, October 2.

Cancer of the upper aerodigestive tract and the large intestine: possible mechanisms. NIH Conference, mechanisms of alcohol associated cancers Chair. 6Th/7th October 2004 Bethesda, Maryland USA.

Member of an International panel on Alcohol and Cancer, International Agency for Reseach and Cancer (IARC), Lyon France, 6th-13th Feb. 2007

Alcoholic Steatohepatitis: established and experimental therapy. Chair together with C.P. Day Workshop, European Association for the study of the liver (EASL) Milano, Italy 24th .- 26th April 2008

Member of a scientific delegation of Baden Württemberg to the
sultanate Brunei 14th to 18th November 2009

Invitation for the 1st Charles Lieber Memorial Symposium during the RSA Congress in San Antonio, Texas USA

ISBRA Congress, Paris 11th to 15th September 2010

German Society for Gastroenterology, DVGS, Stuttgart, September 16, 2010

Extramural Advisor for the NIAAA on Alcohol and Cancer,
Rockville USA (8th-9th June 2010

Faculty Member of the United European Gastroenterology Week
(UEGW) in Barcelona (Spain)

Member of scientific delegation of Baden Württemberg to
Saudi Arabia 23rd to 28th April 2010

Faculty Member of the European Association for the Study of the Liver (EASL), Vienna

Member of a European Panel of the European Association for the Study of the Liver (EASL) for the Guidelines of Alcoholic Liver Disease

Faculty Member of the United European Gastroenterology Week (UEGW) in Stockholm, Sweden

Faculty Member, Ann. Congress of the European Association for the study of the liver (EASL) Berlin, April 2011

Faculty Member of the European Association for the study of the Liver (EASL) Barcelona, Spain, April 2012

Invitation as a ad hoc extramural Advisor to the NIAAA for Alcoholic Hepatitis, Rockville, Maryland, USA 7th to 8th February 2012

Invitation 2012 ISBRA Satellite Symposium Kyoto, Japan
14th September 2012

ISBRA Congress, Sapporo, Japan

Faculty Member of the European Association for the Study of the Liver (EASL) Amsterdam, The Netherlands, 24th - 28th April 2013

Faculty Member of the United European Gastroenterology Week
(UEGW), Berlin, Germany, October 2013

DGVS, Nürnberg

Member of Dissertation Board, Maastrich, The Netherlands
(23rd January 2014)

Faculty Member of the European Association for the Study of the Liver (EASL) London, UK, 9th – 13th April 2014

Guidelines NAFLD, German Society for Digestive and Metabolic Diseases

Faculty Member of the United European Gastroenterology Week
(UEGW) Wien, Austria, October 2014

ESBRA Valencia, Spain

ISBRA, Berlin

Representive of the United European Gastroenterology Week (UEWG), Souzou, VR China, September 2016

Faculty Member of the United European Gastroenterology Week
(UEWG) Barcelona Spain, October 2015

The International Liver Meeting, Amsterdam, The Netherlands
(EASL) April 2017

Gordon Conference on Alcoholic Liver Disease, Ventura, CA, USA March 2017

Charles Lieber Symposium, RSA, Crakow, Poland

Organizer and Speaker, Charles Lieber Memorial Symposium (RSA):San Antonio (2010), Atlanta (2011), San Francisco (2012), Orlando (2013), Seattle (2014), San Antonio (2015), New Orleans (2016), Denver (2017), San Diego (2018), Minneapolis (2019), Virtual (2021), Orlando (2022), Bellevue (2023), Minneapolis (2024)